Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14973691 | 1.00 | LMNA (0.36) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL14973365 | 1.00 | LMNA (0.36) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL14973531 | 1.00 | LMNA (0.36) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL14973348 | 1.00 | LMNA (0.36) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL10597697 | 0.90 | TSHR (0.36) | LMNATSHRALDH1A1 | |
| SCHEMBL10632794 | 0.84 | ANPEP (0.36) | LMNATSHR | |
| SCHEMBL21410063 | 0.82 | TSHR (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL542040 | 0.82 | TSHR (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL22749286 | 0.82 | TSHR (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL21410057 | 0.82 | TSHR (0.50) | LMNATSHRALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550725-B2 | Lipophilic polyalkylenepolyamines by homogeneously catalyzed alcohol amination | BASF SE (DE) | 2017-01-24 | — | — | US | disclosed |
| EP-2782948-B1 | LIPOPHILIC POLYALKYLENE POLYAMINES OBTAINED BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION | BASF SE (DE) | 2016-06-08 | — | — | EP | disclosed |
| US-9328201-B2 | Alkoxylated polyalkylenepolyamines | BASF SE (DE) | 2016-05-03 | — | — | US | disclosed |
| US-8877977-B2 | Synthesis of polyalkylenepolyamines having a low color index by homogeneously catalyzed alcohol amination in the presence of hydrogen | BASF SE (DE) | 2014-11-04 | — | — | US | disclosed |
| US-20140305339-A1 | LIPOPHILIC POLYALKYLENEPOLYAMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION | BASF SE (DE) | 2014-10-16 | — | — | US | disclosed |
| US-20140309460-A1 | INCREASING THE MOLAR MASS OF POLYALKYLENEPOLYAMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION | BASF SE (DE) | 2014-10-16 | — | — | US | disclosed |
| EP-2782949-A1 | SYNTHESIS OF POLYALKYLENE POLYAMINES WITH LOW COLOR INDEX BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION IN THE PRESENCE OF HYDROGEN | BASF SE (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2782947-A1 | INCREASE OF THE MOLAR MASS OF POLYALKYLENE POLYAMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION | BASF SE (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2782950-A1 | ALKOXYLATED POLYALKYLENE POLYAMINES | BASF SE (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2782948-A1 | LIPOPHILIC POLYALKYLENE POLYAMINES OBTAINED BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION | BASF SE (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-20140288265-A1 | ALKOXYLATED POLYALKYLENEPOLYAMINES | BASF SE (DE) | 2014-09-25 | — | — | US | disclosed |
| US-20130137901-A1 | SYNTHESIS OF POLYALKYLENEPOLYAMINES HAVING A LOW COLOR INDEX BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION IN THE PRESENCE OF HYDROGEN | BASF SE (DE) | 2013-05-30 | — | — | US | disclosed |
| WO-2013076024-A1 | ALKOXYLATED POLYALKYLENE POLYAMINES | BASF SE (DE) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013076053-A1 | SYNTHESIS OF POLYALKYLENE POLYAMINES WITH LOW COLOR INDEX BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION IN THE PRESENCE OF HYDROGEN | BASF SE (DE) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013076025-A1 | LIPOPHILIC POLYALKYLENE POLYAMINES OBTAINED BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION | BASF SE (DE) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013076023-A1 | INCREASE OF THE MOLAR MASS OF POLYALKYLENE POLYAMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION | BASF SE (DE) | 2013-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140305339-A1 | LIPOPHILIC POLYALKYLENEPOLYAMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION | ADH5, PNMT, ADH1A | LMNA 1291/4885TSHR 3490/4885ALDH1A1 119/4885 |
| US-20130137901-A1 | SYNTHESIS OF POLYALKYLENEPOLYAMINES HAVING A LOW COLOR INDEX BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION IN THE PRESENCE OF HYDROGEN | ADH1A, PNMT, ADH5 | LMNA 3045/4885TSHR 4407/4885ALDH1A1 30/4885 |
| US-20140309460-A1 | INCREASING THE MOLAR MASS OF POLYALKYLENEPOLYAMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION | PNMT, RNGTT, PCNA | LMNA 3557/4885TSHR 4506/4885ALDH1A1 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.