Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | ULK1 | O75385 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977196 | 0.88 | KIT (0.39) | KITPTGDR2TACR3SMN1; SMN2DGAT1 | |
| SCHEMBL14977224 | 0.87 | KIT (0.39) | KITPTGDR2KDM4ENPC1ALDH1A1 | |
| SCHEMBL14976444 | 0.85 | CSNK1D (0.39) | KITPTGDR2TACR3PPARGROCK2 | |
| SCHEMBL14977379 | 0.82 | DGAT2 (0.42) | KITPTGDR2KDM4ENPC1MAPT | |
| SCHEMBL14977707 | 0.82 | PPARG (0.39) | KITPTGDR2KDM4ENPC1MAPT | |
| SCHEMBL14977623 | 0.82 | PPARG (0.39) | KITPTGDR2KDM4ENPC1MAPT | |
| SCHEMBL14977339 | 0.80 | ROCK2 (0.43) | KITPTGDR2NPC1MAPTPPARG | |
| SCHEMBL14977718 | 0.79 | ROCK2 (0.35) | KITPTGDR2NPC1RAB9ATACR3 | |
| SCHEMBL14977301 | 0.79 | CSNK1D (0.36) | KITPTGDR2NPC1RAB9ATACR3 | |
| SCHEMBL14977582 | 0.78 | CYP2C8 (0.41) | CNR1CNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |