Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIPK4 | Q8NE63 | 3/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14976233 | 0.88 | KIT (0.38) | KITPTGDR2MAPK14SMN1; SMN2DGAT1 | |
| SCHEMBL14977224 | 0.87 | KIT (0.39) | KITPTGDR2SMN1; SMN2CSNK1DCSNK1E | |
| SCHEMBL14976444 | 0.86 | CSNK1D (0.39) | KITPTGDR2CSNK1DCSNK1ETACR3 | |
| SCHEMBL14977707 | 0.85 | PPARG (0.39) | KITPTGDR2MAPK14SMN1; SMN2 | |
| SCHEMBL14977379 | 0.83 | DGAT2 (0.42) | KITPTGDR2SMN1; SMN2 | |
| SCHEMBL14977623 | 0.83 | PPARG (0.39) | KITPTGDR2SMN1; SMN2 | |
| SCHEMBL14977718 | 0.81 | ROCK2 (0.35) | KITPTGDR2SMN1; SMN2CSNK1DCSNK1E | |
| SCHEMBL14977339 | 0.81 | ROCK2 (0.43) | KITPTGDR2 | |
| SCHEMBL14977569 | 0.80 | MAPK14 (0.37) | MAPK14DGAT1 | |
| SCHEMBL14977301 | 0.80 | CSNK1D (0.36) | KITPTGDR2CSNK1DCSNK1ETACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | claimed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |