Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL14976648 | 0.83 | LMNA (0.52) | L3MBTL1LMNAPKMPKLRMEN1 | |
| SCHEMBL25642 | 0.83 | LMNA (0.63) | L3MBTL1LMNAPKMMEN1KMT2A | |
| SCHEMBL29391838 | 0.83 | LMNA (0.63) | L3MBTL1LMNAPKMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7566123 | 0.81 | LMNA (0.61) | L3MBTL1LMNAPKMMEN1KMT2A | |
| SCHEMBL27629181 | 0.81 | LMNA (0.61) | L3MBTL1LMNAPKMMEN1KMT2A | |
| SCHEMBL4013923 | 0.80 | RAPGEF4 (0.63) | L3MBTL1RAPGEF4MEN1KMT2AHTT | |
| SCHEMBL1149006 | 0.77 | LMNA (0.55) | L3MBTL1LMNAPKMMEN1KMT2A | |
| SCHEMBL7608 | 0.77 | CA1 (0.52) | RAPGEF4MEN1KMT2ANR3C1PGR | |
| SCHEMBL1019043 | 0.76 | FABP4 (0.46) | L3MBTL1LMNAPKMMEN1KMT2A | |
| SCHEMBL7013575 | 0.76 | CYP2A6 (0.54) | L3MBTL1LMNAPKMHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000594-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-01-04 | — | — | WO | disclosed |