Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 10/20 | 0.82 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.82 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | LMNA | P02545 | 2/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.82 |
| ▸ | TTR | P02766 | 2/20 | 0.82 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.82 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.82 |
| ▸ | PGR | P06401 | 1/20 | 0.82 |
| ▸ | HTR1A | P08908 | 1/20 | 0.82 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.82 |
| ▸ | AR | P10275 | 1/20 | 0.82 |
| ▸ | MAPT | P10636 | 1/20 | 0.82 |
| ▸ | HPGD | P15428 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tolfenamic Acid SCHEMBL8060884 | 0.90 | MT-CO2 (1.00) | MT-CO2PTGS2MEN1AKR1C3KMT2A | |
| Tolfenamic Acid SCHEMBL25190 | 0.90 | MT-CO2 (1.00) | MT-CO2PTGS2MEN1AKR1C3KMT2A | |
| Tolfenamic Acid SCHEMBL29389998 | 0.90 | MT-CO2 (1.00) | MT-CO2PTGS2MEN1AKR1C3KMT2A | |
| Tolfenamic Acid SCHEMBL29484181 | 0.90 | MT-CO2 (1.00) | MT-CO2PTGS2MEN1AKR1C3KMT2A | |
| Tolfenamic Acid SCHEMBL27540385 | 0.89 | MT-CO2 (0.97) | MT-CO2PTGS2MEN1AKR1C3KMT2A | |
| Tolfenamic Acid SCHEMBL10619715 | 0.85 | MT-CO2 (0.89) | MT-CO2PTGS2MEN1AKR1C3KMT2A | |
| Tolfenamic Acid SCHEMBL28095333 | 0.84 | MT-CO2 (0.86) | MT-CO2PTGS2MEN1AKR1C3KMT2A | |
| Tolfenamic Acid SCHEMBL28229025 | 0.82 | MT-CO2 (0.82) | MT-CO2PTGS2MEN1AKR1C3KMT2A | |
| SCHEMBL30593456 | 0.79 | MT-CO2 (0.73) | MT-CO2PTGS2MEN1AKR1C3KMT2A | |
| SCHEMBL13465152 | 0.79 | MT-CO2 (0.73) | MT-CO2PTGS2MEN1AKR1C3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296716-B2 | Androgen receptor ligands | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIV. TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2016-03-29 | — | — | US | disclosed |
| US-20140357682-A1 | ANDROGEN RECEPTOR LIGANDS | The Provost, Fellows, Foundation Scholars, & the Other Members of Board, of The College of the Holy (IE) | 2014-12-04 | — | — | US | disclosed |
| EP-2782643-A1 | ANDROGEN RECEPTOR LIGANDS | The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin (IE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013076275-A1 | ANDROGEN RECEPTOR LIGANDS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIV.TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2013-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357682-A1 | ANDROGEN RECEPTOR LIGANDS | AR, NR5A1, SHBG | MT-CO2 3388/4885PTGS2 1012/4885MEN1 4657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.