Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CCNH | P51946 | 1/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14976040 | 0.87 | HDAC3 (0.47) | PGRFFAR4HDAC1HDAC8PTPN2 | |
| SCHEMBL14976775 | 0.86 | HTR6 (0.53) | FFAR4GAAKMT2ACACNA1HCACNA1B | |
| SCHEMBL14977115 | 0.81 | HTR6 (0.55) | PGRGAAHDAC1HDAC8KMT2A | |
| SCHEMBL14976807 | 0.81 | CA12 (0.49) | FFAR1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL14976472 | 0.80 | CACNA1B (0.43) | HSD17B2FFAR1FFAR4GAACACNA1H | |
| SCHEMBL13629410 | 0.77 | HSD17B2 (0.61) | HSD17B2NR3C1PGRARESR2 | |
| SCHEMBL14976733 | 0.76 | HTR7 (0.47) | PTPN2PTPN1PTPN5KMT2AHIF1A | |
| SCHEMBL13615168 | 0.74 | HSD17B2 (0.61) | HSD17B2NR3C1PGRARESR2 | |
| SCHEMBL7572806 | 0.72 | NR3C1 (0.69) | HSD17B2NR3C1PGRARESR2 | |
| SCHEMBL7573925 | 0.71 | HSD17B2 (0.79) | HSD17B2NR3C1PGRARESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013076590-A1 | BENZOTHIAZINE COMPOUNDS AS H3 RECEPTOR LIGANDS | OXYGEN HEALTHCARE RESEARCH PVT. LTD (IN) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013076590-A1 | BENZOTHIAZINE COMPOUNDS AS H3 RECEPTOR LIGANDS | OXYGEN HEALTHCARE RESEARCH PVT. LTD (IN) | 2013-05-30 | — | — | WO | disclosed |