Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.69 |
| ▸ | PGR | P06401 | 1/20 | 0.69 |
| ▸ | AR | P10275 | 1/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.69 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762909 | 0.88 | PGR (0.77) | NR3C1PGRARESR2HSD17B2 | |
| SCHEMBL7572556 | 0.87 | PGR (0.67) | NR3C1PGRARESR2HSD17B2 | |
| SCHEMBL97543 | 0.87 | NR3C1 (0.67) | NR3C1PGRARESR2HSD17B2 | |
| SCHEMBL5037026 | 0.84 | NR3C1 (0.64) | NR3C1PGRARESR2HSD17B2 | |
| SCHEMBL7573925 | 0.81 | HSD17B2 (0.79) | NR3C1PGRARESR2HSD17B2 | |
| SCHEMBL7571567 | 0.81 | HSD17B2 (0.63) | NR3C1PGRARESR2HSD17B2 | |
| SCHEMBL9517099 | 0.81 | TSHR (0.69) | NR3C1PGRARESR2HSD17B2 | |
| SCHEMBL7577535 | 0.81 | CA1 (0.65) | ARHDAC1HDAC8CA1CA2 | |
| SCHEMBL7833934 | 0.80 | PGR (0.63) | NR3C1PGRARESR2HSD17B2 | |
| SCHEMBL7594309 | 0.80 | KMT2A (0.63) | NR3C1PGRARESR2HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |