Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | S100B | P04271 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977606 | 0.93 | MAPK14 (0.41) | MAPK14NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL14977598 | 0.93 | CNR1 (0.42) | MAPK14NPC1RAB9ALMNACNR1 | |
| SCHEMBL14977625 | 0.93 | RIPK2 (0.36) | MAPK14NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL14986303 | 0.90 | ROCK2 (0.37) | MAPK14LMNATHRBLCK | |
| SCHEMBL14977604 | 0.88 | MAPK14 (0.36) | MAPK14MAPT | |
| SCHEMBL14977618 | 0.87 | LHCGR (0.41) | MAPK14NPC1RAB9ALMNATP53 | |
| SCHEMBL14977610 | 0.86 | DGAT2 (0.38) | MAPK14NPC1RAB9ALMNATHRB | |
| SCHEMBL14977581 | 0.85 | MAPK14 (0.39) | MAPK14MAPT | |
| SCHEMBL14977569 | 0.85 | MAPK14 (0.37) | MAPK14MAPT | |
| SCHEMBL14976867 | 0.85 | ROCK2 (0.38) | MAPK14ALDH1A1RIPK2LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | claimed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |