Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977688 | 0.91 | PPARG (0.38) | LHCGRMAPK14MAPTTP53CSNK1E | |
| SCHEMBL14977606 | 0.91 | MAPK14 (0.41) | MAPK14MAPTNPC1RAB9ADGAT2 | |
| SCHEMBL14977625 | 0.91 | RIPK2 (0.36) | MAPK14MAPTNPC1HTTRAB9A | |
| SCHEMBL14977138 | 0.87 | MAPK14 (0.37) | MAPK14MAPTTP53NPC1RAB9A | |
| SCHEMBL14977598 | 0.85 | CNR1 (0.42) | MAPK14TP53NPC1RAB9ALMNA | |
| SCHEMBL14977610 | 0.84 | DGAT2 (0.38) | MAPK14MAPTNPC1RAB9ALMNA | |
| SCHEMBL14977569 | 0.83 | MAPK14 (0.37) | MAPK14MAPTDGAT2 | |
| SCHEMBL14977581 | 0.83 | MAPK14 (0.39) | MAPK14MAPT | |
| SCHEMBL14976867 | 0.83 | ROCK2 (0.38) | MAPK14 | |
| SCHEMBL14977707 | 0.83 | PPARG (0.39) | MAPK14MAPTNPC1LMNADGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | claimed |
| WO-2013075173-A1 | COMPOUNDS FOR THE TREATMENT OF HCV | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-05-30 | — | — | WO | disclosed |