Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783152 | 0.76 | LMNA (0.55) | HPGDLMNATSHRMEN1KMT2A | |
| SCHEMBL14782820 | 0.74 | LMNA (0.48) | HPGDLMNATSHRKMT2AALDH1A1 | |
| SCHEMBL14782977 | 0.73 | HPGD (0.55) | HPGDLMNATSHRKDM4EALDH1A1 | |
| SCHEMBL14782827 | 0.71 | ERCC1 (0.53) | HPGDLMNATSHRMEN1KMT2A | |
| SCHEMBL9932144 | 0.70 | PTGES (0.57) | HPGDLMNATSHRSMN1; SMN2CYP4F2 | |
| SCHEMBL14782792 | 0.70 | PTGES (0.57) | HPGDLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL14782775 | 0.70 | PKM (0.55) | HPGDLMNATSHRKMT2AKDM4E | |
| SCHEMBL12332820 | 0.69 | CYP4F2 (0.58) | HPGDLMNATSHRMEN1KMT2A | |
| SCHEMBL14969490 | 0.69 | TSHR (0.57) | HPGDLMNATSHRALDH1A1GAA | |
| SCHEMBL14783086 | 0.69 | HPGD (0.52) | HPGDLMNATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072825-A1 | PHTALAZINONE DERIVATIVES AS MPEGS -1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-05-23 | — | — | WO | disclosed |