Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14983677 | 0.83 | RAB9A (0.42) | RAB9ANPSR1KDM4EKLK7KMT2A | |
| SCHEMBL12338165 | 0.80 | KDM4E (0.34) | RAB9ANPSR1KDM4EKLK7AURKA | |
| SCHEMBL12503461 | 0.76 | EGLN1 (0.40) | RAB9ANPSR1KDM4EKLK7CA12 | |
| SCHEMBL14612959 | 0.72 | ALDH1A1 (0.34) | RAB9ANPSR1AURKAKMT2AMEN1 | |
| SCHEMBL15601828 | 0.71 | CA12 (0.38) | RAB9AKDM4EKLK7KMT2AMEN1 | |
| SCHEMBL12316235 | 0.70 | THRA (0.34) | RAB9AKDM4EKLK7KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL28160879 | 0.70 | DHFR (0.50) | — | |
| SCHEMBL12412659 | 0.69 | SMN1; SMN2 (0.43) | ALDH1A1PLAUEGLN1SMN1; SMN2 | |
| SCHEMBL23320696 | 0.68 | RAB9A (0.41) | RAB9AKDM4EALDH1A1TSHRCA12 | |
| SCHEMBL21963629 | 0.68 | KMT2A (0.68) | RAB9AKDM4EKLK7KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008032171-A1 | DIBENZOFURAN DERIVATIVES AS INHIBITORS OF PDE-4 AND PDE-10 | MATRIX LABORATORIES LTD. (DE) | 2008-03-20 | — | — | WO | disclosed |