Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14985280 | 0.93 | SMN1; SMN2 (0.70) | GAASMN1; SMN2LMNANPC1POLB | |
| SCHEMBL14975698 | 0.91 | SMN1; SMN2 (0.72) | GAASMN1; SMN2LMNANPC1POLB | |
| SCHEMBL11446232 | 0.79 | KMT2A (0.67) | GAASMN1; SMN2LMNAPOLBMEN1 | |
| SCHEMBL6842122 | 0.79 | HDAC2 (0.80) | SMN1; SMN2LMNANPC1MEN1KMT2A | |
| SCHEMBL14985314 | 0.77 | GAA (0.64) | GAASMN1; SMN2LMNANPC1MEN1 | |
| SCHEMBL14976194 | 0.77 | LMNA (0.67) | GAASMN1; SMN2LMNANPC1MEN1 | |
| SCHEMBL14976630 | 0.76 | KMT2A (0.63) | GAASMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL6270935 | 0.75 | ALDH1A1 (0.77) | GAASMN1; SMN2NPC1POLBMEN1 | |
| SCHEMBL29356619 | 0.75 | ALDH1A1 (0.77) | GAASMN1; SMN2NPC1POLBMEN1 | |
| SCHEMBL11716101 | 0.74 | MTNR1B (0.68) | GAASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |