Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15871311 | 0.84 | PTGS2 (0.35) | PTGS2CYP3A4TDP1L3MBTL1KDM4E | |
| SCHEMBL14985415 | 0.84 | PTGS2 (0.35) | PTGS2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL14985437 | 0.84 | RAB9A (0.33) | PTGS2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL14351415 | 0.81 | PTGS2 (0.39) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL1323842 | 0.79 | PTGS2 (0.48) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL3555634 | 0.79 | PTGS2 (0.48) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL2012315 | 0.79 | PTGS2 (0.48) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL196514 | 0.79 | PTGS2 (0.48) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL14478041 | 0.79 | CASP3 (0.33) | PTGS2KDM4E | |
| SCHEMBL30475751 | 0.77 | DRD2 (0.35) | ADORA3KDM4EALDH1A1HSD17B10ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |
| US-9249102-B2 | Anthelmintic compounds and compositions and method of using thereof | MERIAL, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-9040655-B2 | Direct CH arylation method using palladium-based catalyst | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-05-26 | — | — | US | disclosed |
| US-9040655-B2 | Direct CH arylation method using palladium-based catalyst | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-05-26 | — | — | US | disclosed |
| US-20140142263-A1 | DIRECT CH ARYLATION METHOD USING PALLADIUM-BASED CATALYST | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-05-22 | — | — | US | disclosed |
| US-20140142263-A1 | DIRECT CH ARYLATION METHOD USING PALLADIUM-BASED CATALYST | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-05-22 | — | — | US | disclosed |
| US-20140142114-A1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2014-05-22 | — | — | US | disclosed |
| WO-2013077615-A1 | DIRECT CH ARYLATION METHOD USING PALLADIUM-BASED CATALYST | 광주과학기술원 (KR) | 2013-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142114-A1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | CYP3A5, ABCC5, CXXC5 | PTGS2 1490/4885CYP3A4 58/4885PLA2G4A 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.