SCHEMBL1498710

SCHEMBL1498710

CCCCCCCNc1ccc(N)c(C2CCCCC2)c1C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 6/20 0.38
CNR2 P34972 5/20 0.38
NAAA Q02083 1/20 0.35
EPHX1 P07099 8/20 0.34
EPHX2 P34913 2/20 0.34
PRSS1 P07477 2/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1498815 0.94 TLR8 (0.37) CNR1CNR2
SCHEMBL1498787 0.84 CNR1 (0.39) CNR1CNR2NAAAEPHX1EPHX2
SCHEMBL3688474 0.83 ALOX15 (0.37) CNR1CNR2ALDH1A1LMNA
SCHEMBL1498651 0.81 KCNH3 (0.46) CNR1CNR2EPHX1MEN1ALDH1A1
SCHEMBL1498718 0.78 TLR8 (0.35) CNR1CNR2MEN1KMT2A
SCHEMBL1498690 0.76 CNR1 (0.44) CNR1CNR2NAAAEPHX1EPHX2
SCHEMBL1498738 0.76 IDO1 (0.35) ALDH1A1
SCHEMBL5199069 0.73 CNR1 (0.38) CNR1CNR2ALDH1A1KMT2A
SCHEMBL1498733 0.72 KDM4E (0.34)
SCHEMBL247757 0.72 TDO2 (0.38) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011506452-A 2011-03-03 JP claimed
EP-2240559-A2 CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS Chemtura Corporation (US) 2010-10-20 EP claimed
WO-2009076090-A2 CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS CHEMTURA CORPORATION (US) 2009-06-18 WO claimed
EP-2240559-A2 CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS Chemtura Corporation (US) 2010-10-20 EP disclosed
WO-2009076090-A2 CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS CHEMTURA CORPORATION (US) 2009-06-18 WO disclosed