Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PLEC | Q15149 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498815 | 0.85 | TLR8 (0.37) | ALOX15MAPTCNR1CNR2 | |
| SCHEMBL1498738 | 0.83 | IDO1 (0.35) | ALOX15KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL1498710 | 0.83 | CNR1 (0.38) | ALDH1A1LMNACNR1CNR2 | |
| SCHEMBL28273169 | 0.81 | KDM4E (0.36) | ALOX15KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL1498733 | 0.79 | KDM4E (0.34) | ALOX15KDM4EGAAMAPTADK | |
| SCHEMBL3692132 | 0.78 | TDO2 (0.38) | KDM4EGAAMAPTALDH1A1GFER | |
| SCHEMBL4482096 | 0.78 | TDO2 (0.38) | KDM4EGAAMAPTALDH1A1GFER | |
| SCHEMBL247757 | 0.78 | TDO2 (0.38) | KDM4EGAAMAPTALDH1A1GFER | |
| SCHEMBL3698113 | 0.75 | ALOX15 (0.32) | ALOX15ALDH1A1 | |
| SCHEMBL1498685 | 0.73 | MAPT (0.44) | ALOX15KDM4EGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |