Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698113 | 0.85 | ALOX15 (0.32) | ALOX15 | |
| SCHEMBL28273169 | 0.83 | KDM4E (0.36) | KDM4EGAAMAPTALOX15ADK | |
| SCHEMBL1498738 | 0.81 | IDO1 (0.35) | KDM4EGAAMAPTALOX15IDO1 | |
| SCHEMBL247757 | 0.80 | TDO2 (0.38) | KDM4EGAAMAPTADKTDO2 | |
| SCHEMBL4482096 | 0.80 | TDO2 (0.38) | KDM4EGAAMAPTADKTDO2 | |
| SCHEMBL3692132 | 0.80 | TDO2 (0.38) | KDM4EGAAMAPTADKTDO2 | |
| SCHEMBL3688474 | 0.79 | ALOX15 (0.37) | KDM4EGAAMAPTALOX15ADK | |
| SCHEMBL1498685 | 0.74 | MAPT (0.44) | KDM4EGAAMAPTALOX15HDAC1 | |
| SCHEMBL1498710 | 0.72 | CNR1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL3502250 | 0.71 | IDO1 (0.39) | KDM4EGAAALOX15IDO1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011506452-A | — | — | 2011-03-03 | — | — | JP | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |