Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | F2R | P25116 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498717 | 0.95 | F2R (0.38) | CNR2MEN1KMT2APOLBF2R | |
| SCHEMBL1498709 | 0.84 | ABL1 (0.40) | ABL1CNR2MEN1KMT2AKCNH3 | |
| SCHEMBL1498813 | 0.78 | RAB9A (0.38) | ABL1CNR2MEN1KMT2AEPHX1 | |
| SCHEMBL9186434 | 0.76 | ALDH1A1 (0.47) | ABL1MEN1KMT2AKCNH3EPHX1 | |
| SCHEMBL8862298 | 0.75 | ABL1 (0.44) | ABL1KCNH3EPHX1F2RHDAC11 | |
| SCHEMBL8552475 | 0.74 | KDM4E (0.47) | ABL1CNR2KCNH3EPHX1F2R | |
| SCHEMBL3662823 | 0.73 | ABL1 (0.54) | ABL1KCNH3EPHX1F2RHDAC11 | |
| SCHEMBL4476457 | 0.72 | ICMT (0.43) | CNR2MEN1KMT2AICMTALB | |
| SCHEMBL21799446 | 0.71 | TSHR (0.50) | ABL1MEN1KMT2AKCNH3EPHX1 | |
| SCHEMBL21799643 | 0.71 | TSHR (0.50) | ABL1MEN1KMT2AKCNH3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011506452-A | — | — | 2011-03-03 | — | — | JP | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |