SCHEMBL14993138

SCHEMBL14993138

COc1ccc(COC(=O)C(=O)C2CCCCC2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.55
FKBP1A P62942 1/20 0.54
ALDH1A1 P00352 4/20 0.51
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
HPGD P15428 1/20 0.49
CYP2C19 P33261 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
CACNA1B Q00975 2/20 0.47
MAPT P10636 2/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23929358 0.86 LMNA (0.50) ALDH1A1HPGDSMN1; SMN2NPC1RAB9A
SCHEMBL8587581 0.85 ALDH1A1 (0.63) EPHX2ALDH1A1HPGDSMN1; SMN2NPC1
SCHEMBL27793138 0.84 ALDH1A1 (0.61) EPHX2ALDH1A1HPGDSMN1; SMN2NPC1
SCHEMBL7637109 0.82 ALDH1A1 (0.53) EPHX2FKBP1AALDH1A1CYP2C19SMN1; SMN2
SCHEMBL7641957 0.82 ALDH1A1 (0.53) EPHX2FKBP1AALDH1A1CYP2C19SMN1; SMN2
SCHEMBL2706422 0.82 ALDH1A1 (0.53) EPHX2FKBP1AALDH1A1CYP2C19SMN1; SMN2
SCHEMBL28813611 0.81 ALDH1A1 (0.57) EPHX2ALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL16321255 0.81 EPHX2 (0.52) EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL304689 0.80 FKBP1A (0.53) FKBP1AALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL3758807 0.79 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2822682-B1 MICROCAPSULES AND USES THEREOF FIRMENICH & CIE (CH) 2017-04-26 EP claimed
CN-103958047-B Microcapsules and their use 弗门尼舍有限公司 2017-03-01 CN claimed
US-9334464-B2 Microcapsules and uses thereof FIRMENICH SA (CH) 2016-05-10 US claimed
EP-2822682-A1 MICROCAPSULES AND USES THEREOF Firmenich SA (CH) 2015-01-14 EP claimed
US-20140323376-A1 MICROCAPSULES AND USES THEREOF FIRMENICH SA (CH) 2014-10-30 US claimed
CN-103958047-A Microcapsules and their use FIRMENICH & CIE 2014-07-30 CN claimed
WO-2013079435-A1 MICROCAPSULES AND USES THEREOF FIRMENICH SA (CH) 2013-06-06 WO claimed
US-12264295-B2 Encapsulated pro-perfume compounds FIRMENICH SA (CH) 2025-04-01 US disclosed
US-20230093639-A1 PERFUME SYSTEM FOR PERFUMED CONSUMER PRODUCT FIRMENICH SA (CH) 2023-03-23 US disclosed
US-20230032098-A1 ENCAPSULATED PRO-PERFUME COMPOUNDS FIRMENICH SA (CH) 2023-02-02 US disclosed
CN-115175658-A Perfume system for perfumed consumer products 弗门尼舍有限公司 2022-10-11 CN disclosed
EP-3942009-A1 ENCAPSULATED PRO-PERFUME COMPOUNDS Firmenich SA (CH) 2022-01-26 EP disclosed
CN-113614214-A Encapsulated pro-fragrance compounds 弗门尼舍有限公司 2021-11-05 CN disclosed
US-9334464-B2 Microcapsules and uses thereof FIRMENICH SA (CH) 2016-05-10 US disclosed
EP-2822682-A1 MICROCAPSULES AND USES THEREOF Firmenich SA (CH) 2015-01-14 EP disclosed
US-20140323376-A1 MICROCAPSULES AND USES THEREOF FIRMENICH SA (CH) 2014-10-30 US disclosed
CN-103958047-A Microcapsules and their use FIRMENICH & CIE 2014-07-30 CN disclosed
WO-2013079435-A1 MICROCAPSULES AND USES THEREOF FIRMENICH SA (CH) 2013-06-06 WO disclosed
CN-1160306-C Slow release of fragrant compounds is perfoumery using 2-benzoyl benzoates, 2-alkanoyl benzoates or alpha-keto esters 2004-08-04 CN disclosed
CN-1302286-A Slow release of fragrant compounds is perfoumery using 2-benzoyl benzoates, 2-alkanoyl benzoates or alpha-keto esters FIRMENICH & CIE (CH) 2001-07-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230093639-A1 PERFUME SYSTEM FOR PERFUMED CONSUMER PRODUCT PORCN, FAAH2, FASN EPHX2 469/4885FKBP1A 4015/4885ALDH1A1 817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.