Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.36 |
| ▸ | HTR2A | P28223 | 7/20 | 0.36 |
| ▸ | HTR2B | P41595 | 7/20 | 0.36 |
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | HTR1D | P28221 | 5/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143507 | 0.76 | HTR2C (0.45) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL9626819 | 0.68 | PKM (0.39) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL26130378 | 0.65 | HTR2A (0.42) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL4708855 | 0.65 | DYRK1A (0.40) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL5785528 | 0.65 | MAPT (0.40) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL8889464 | 0.63 | HTR2C (0.39) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL13035776 | 0.62 | HTR2C (0.43) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL19827780 | 0.62 | MTNR1A (0.39) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL19827779 | 0.62 | MTNR1A (0.41) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL19756703 | 0.61 | CYP2A6 (0.37) | HTR2CHTR2AHTR2BHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785722-A1 | TOCOTRIENOL DERIVATIVES AND ASSOCIATED METHODS | First Tech International Limited (CN) | 2014-10-08 | — | — | EP | claimed |
| WO-2013082570-A1 | TOCOTRIENOL DERIVATIVES AND ASSOCIATED METHODS | FIRST TECH INTERNATIONAL LIMITED (CN) | 2013-06-06 | — | — | WO | claimed |
| EP-2785722-A1 | TOCOTRIENOL DERIVATIVES AND ASSOCIATED METHODS | First Tech International Limited (CN) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013082570-A1 | TOCOTRIENOL DERIVATIVES AND ASSOCIATED METHODS | FIRST TECH INTERNATIONAL LIMITED (CN) | 2013-06-06 | — | — | WO | disclosed |