Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 7/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.36 |
| ▸ | HTR1D | P28221 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143507 | 0.76 | HTR2C (0.45) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL9627709 | 0.73 | BRD4 (0.36) | PKMNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL9626749 | 0.72 | PDE4D (0.38) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL15964648 | 0.71 | MAPT (0.53) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9095936 | 0.69 | DRD2 (0.35) | HTR2AHTR2BNPC1MAPK13MAPK12 | |
| Hydrochloric Acid SCHEMBL9095687 | 0.68 | DRD2 (0.35) | HTR2AHTR2BNPC1MAPK13MAPK12 | |
| SCHEMBL14993793 | 0.68 | HTR2C (0.36) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL4708855 | 0.68 | DYRK1A (0.40) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL4786408 | 0.67 | DRD2 (0.37) | PKMHTR2AHTR2BDRD2MMP12 | |
| SCHEMBL23461782 | 0.67 | KIF11 (0.36) | PKMNOTUMNPC1MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093339-A | Anticoagulant, hypotensive, antiangina, antiasthma, antiulcer, anti-platelet activating factor | KODAMA KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0355689-A2 | Pyrano [f] quinoline derivatives and pharmaceutical compositions containing the same | KODAMA KABUSHIKI KAISHA (JP) | 1990-02-28 | — | — | EP | disclosed |