Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7372571 | 0.81 | MAOA (0.65) | MAOAMAOBPTGS2ALDH1A1LMNA | |
| SCHEMBL5390967 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EGAATSHR | |
| SCHEMBL30384869 | 0.80 | RAB9A (0.58) | ALDH1A1LMNATP53TSHRROCK2 | |
| SCHEMBL1106938 | 0.79 | MAOA (0.67) | MAOAMAOBPTGS2ALDH1A1LMNA | |
| SCHEMBL14393335 | 0.79 | KDM4E (0.61) | MAOAMAOBPTGS2ALDH1A1LMNA | |
| SCHEMBL27920780 | 0.78 | ALDH1A1 (0.55) | MAOBALDH1A1LMNAKDM4ECYP1A2 | |
| SCHEMBL28796093 | 0.76 | CA1 (0.62) | ALDH1A1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6030061 | 0.76 | MAOA (0.58) | MAOAMAOBPTGS2ALDH1A1LMNA | |
| SCHEMBL28208156 | 0.76 | KDM4E (0.57) | MAOAMAOBPTGS2ALDH1A1LMNA | |
| SCHEMBL9402804 | 0.75 | MLYCD (0.47) | CA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785714-A1 | IMPROVED MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR | Taivex Therapeutics Corporation (TW) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013082324-A1 | IMPROVED MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR | TAIVEX THERAPEUTICS CORPORATION (TW) | 2013-06-06 | — | — | WO | disclosed |