SCHEMBL1499579

SCHEMBL1499579

CC(C)C[C@H](NC(=O)[C@H](N)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)C(Cl)C(=O)C(Cl)C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](N)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 7/20 0.40
▸ OPRM1 P35372 3/20 0.40
▸ FURIN P09958 2/20 0.39
▸ PCSK6 P29122 1/20 0.39
▸ NMT2 O60551 1/20 0.38
▸ NMT1 P30419 1/20 0.38
▸ CPB2 Q96IY4 3/20 0.36
▸ DPP4 P27487 1/20 0.36
▸ DPP8 Q6V1X1 1/20 0.36
▸ DPP9 Q86TI2 1/20 0.36
▸ DPP7 Q9UHL4 1/20 0.36
▸ ERAP2 Q6P179 3/20 0.36
▸ ERAP1 Q9NZ08 2/20 0.36
▸ LNPEP Q9UIQ6 2/20 0.36
▸ PSMB5 P28074 1/20 0.35
▸ PSMB2 P49721 1/20 0.35
▸ NPY4R P50391 2/20 0.33
▸ NPY1R P25929 1/20 0.33
▸ NPY2R P49146 1/20 0.33
▸ NPY5R Q15761 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1711325 0.85 CPB2 (0.47) OPRK1OPRM1FURINPCSK6CPB2
SCHEMBL1711738 0.85 CPB2 (0.47) OPRK1OPRM1FURINPCSK6CPB2
SCHEMBL1711732 0.85 CPB2 (0.47) OPRK1OPRM1FURINPCSK6CPB2
SCHEMBL1711321 0.85 CPB2 (0.47) OPRK1OPRM1FURINPCSK6CPB2
Hydrochloric Acid SCHEMBL11366046 0.84 CPB2 (0.47) OPRK1OPRM1FURINPCSK6CPB2
SCHEMBL10652275 0.84 NMT2 (0.43) OPRK1OPRM1FURINPCSK6NMT2
SCHEMBL30284335 0.82 CPB2 (0.45) OPRK1OPRM1FURINPCSK6NMT2
SCHEMBL31257001 0.81 CPB2 (0.45) OPRK1OPRM1CPB2ERAP2ERAP1
SCHEMBL11011274 0.79 OPRK1 (0.38) OPRK1OPRM1FURINPCSK6NMT2
SCHEMBL11011268 0.79 OPRK1 (0.38) OPRK1OPRM1FURINPCSK6NMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268604-B2 Compositions for forming immobilized biological layers for sensing ABBOTT POINT OF CARE INC. (US) 2012-09-18 — — US claimed
JP-2011508221-A — — 2011-03-10 — — JP claimed
US-20100255120-A1 COMPOSITIONS FOR FORMING IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC. 2010-10-07 — — US claimed
EP-2225388-A1 COMPOSITIONS FOR FORMING IMMOBIIZED BIOLOGICAL LAYERS FOR SENSING Abbott Point Of Care, Inc. (US) 2010-09-08 — — EP claimed
WO-2009082699-A1 COMPOSITIONS FOR FORMING IMMOBIIZED BIOLOGICAL LAYERS FOR SENSING I-STAT CORPORATION (US) 2009-07-02 — — WO claimed
US-9441259-B2 Formation of immobilized biological layers for sensing ABBOTT POINT OF CARE INC. (US) 2016-09-13 — — US disclosed
EP-2225388-B1 COMPOSITIONS FOR FORMING IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC (US) 2016-03-30 — — EP disclosed
US-20150275261-A1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC. (US) 2015-10-01 — — US disclosed
US-8986526-B2 Formation of immobilized biological layers for sensing ABBOTT POINT OF CARE INC. (US) 2015-03-24 — — US disclosed
EP-2235513-B1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC (US) 2014-05-07 — — EP disclosed
US-20130112558-A1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC. (US) 2013-05-09 — — US disclosed
US-8389042-B2 Formation of immobilized biological layers for sensing ABBOTT POINT OF CARE INC. (US) 2013-03-05 — — US disclosed
US-8268604-B2 Compositions for forming immobilized biological layers for sensing ABBOTT POINT OF CARE INC. (US) 2012-09-18 — — US disclosed
US-8241697-B2 Formation of immobilized biological layers for sensing ABBOTT POINT OF CARE INC. (US) 2012-08-14 — — US disclosed
US-20100255120-A1 COMPOSITIONS FOR FORMING IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC. 2010-10-07 — — US disclosed
EP-2235513-A1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING Abbott Point Of Care, Inc. (US) 2010-10-06 — — EP disclosed
EP-2225388-A1 COMPOSITIONS FOR FORMING IMMOBIIZED BIOLOGICAL LAYERS FOR SENSING Abbott Point Of Care, Inc. (US) 2010-09-08 — — EP disclosed
WO-2009105145-A1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING I-STAT CORPORATION (US) 2009-08-27 — — WO disclosed
WO-2009082699-A1 COMPOSITIONS FOR FORMING IMMOBIIZED BIOLOGICAL LAYERS FOR SENSING I-STAT CORPORATION (US) 2009-07-02 — — WO disclosed
US-20090159442-A1 FORMATION OF IMMOBILIZED BIOLOGICAL LAYERS FOR SENSING ABBOTT POINT OF CARE INC. 2009-06-25 — — US disclosed
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