Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835032 | 1.00 | MAPT (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL29093262 | 0.90 | MAPT (0.46) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL2140974 | 0.89 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL308082 | 0.89 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL24067699 | 0.89 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL25329304 | 0.89 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL308083 | 0.89 | MAPT (0.59) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL24378366 | 0.87 | MAPT (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL25340359 | 0.87 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Water SCHEMBL8124987 | 0.87 | MAPT (0.57) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174623-A1 | Organosulfur compounds for the prevention and treatment of neurodegenerative diseases | Allium Vitalis, Inc. | 2017-06-22 | — | — | US | disclosed |
| US-20170100349-A1 | ORGANOSULFUR COMPOUNDS FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES | OTT DAVID MICHAEL (US) | 2017-04-13 | — | — | US | disclosed |
| US-9562007-B2 | Organosulfur compounds for the prevention and treatment of neurodegenerative diseases | ALLIUM VITALIS INC. (US) | 2017-02-07 | — | — | US | disclosed |
| US-9456999-B2 | Organosulfur compounds for the prevention and treatment of neurodegenerative diseases | Allium Vitalis, Inc. (US) | 2016-10-04 | — | — | US | disclosed |
| US-20140050677-A1 | Personal care and medicinal products incorporating bound organosulfur groups | OTT DAVID MICHAEL (US) | 2014-02-20 | — | — | US | disclosed |
| US-20130165515-A1 | Organosulfur Compounds for the Prevention and Treatment of Neurodegenerative Diseases | ALLIUM VITALIS INC. | 2013-06-27 | — | — | US | disclosed |
| US-20130143967-A1 | Organosulfur compounds for the prevention and treatment of neurodegenerative diseases | ALLIUM VITALIS INC. | 2013-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170100349-A1 | ORGANOSULFUR COMPOUNDS FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES | SNCA, PARK7, TST | MAPT 49/4885KDM4E 4177/4885THRB 4614/4885 |
| US-20130143967-A1 | Organosulfur compounds for the prevention and treatment of neurodegenerative diseases | SNCA, PARK7, TST | MAPT 80/4885KDM4E 3942/4885THRB 4682/4885 |
| US-20130165515-A1 | Organosulfur Compounds for the Prevention and Treatment of Neurodegenerative Diseases | SNCA, PARK7, TST | MAPT 49/4885KDM4E 4177/4885THRB 4614/4885 |
| US-20140050677-A1 | Personal care and medicinal products incorporating bound organosulfur groups | GPX4, LPO, GPX1 | MAPT 3287/4885KDM4E 2280/4885THRB 3633/4885 |
| US-20170174623-A1 | Organosulfur compounds for the prevention and treatment of neurodegenerative diseases | SNCA, PARK7, TARDBP | MAPT 30/4885KDM4E 3833/4885THRB 4466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.