SCHEMBL15025583

SCHEMBL15025583

CCCCN1CC1C(=O)OCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.34
HPGD P15428 1/20 0.34
ATM Q13315 1/20 0.34
MAPK1 P28482 2/20 0.33
KDM4E B2RXH2 1/20 0.33
OGA O60502 1/20 0.33
ALDH1A1 P00352 2/20 0.32
GBA2 Q9HCG7 8/20 0.32
UGCG Q16739 3/20 0.32
GAA P10253 3/20 0.32
MGAM O43451 2/20 0.32
SI P14410 2/20 0.32
AGL P35573 2/20 0.32
GBA1 P04062 1/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16283147 0.95 HPGD (0.31) L3MBTL1HPGDATM
SCHEMBL15025630 0.95 HPGD (0.31) L3MBTL1HPGDATM
SCHEMBL16281911 0.89
SCHEMBL15032478 0.86 ALDH1A1 (0.35) KDM4EALDH1A1MEN1LMNAKMT2A
SCHEMBL16307662 0.86 ALDH1A1 (0.35) KDM4EALDH1A1MEN1LMNAKMT2A
SCHEMBL1144589 0.81 CYP3A4 (0.32) OGAGAAMGAM
SCHEMBL15025256 0.79 MEN1 (0.41) L3MBTL1HPGDATMMAPK1KDM4E
SCHEMBL15025628 0.79 MEN1 (0.41) L3MBTL1HPGDATMMAPK1KDM4E
SCHEMBL16281908 0.76 ALDH1A1 (0.35) L3MBTL1HPGDATMMAPK1KDM4E
SCHEMBL16307235 0.74 ALDH1A1 (0.34) KDM4EALDH1A1GAAMGAMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9321792-B2 Hydrolysable silanes DOW CORNING CORPORATION (US) 2016-04-26 US disclosed
US-9321792-B2 Hydrolysable silanes DOW CORNING CORPORATION (US) 2016-04-26 US disclosed
US-20140364627-A1 Hydrolysable Silanes DOW SILICONES CORPORATION 2014-12-11 US disclosed
US-20140364627-A1 Hydrolysable Silanes DOW SILICONES CORPORATION 2014-12-11 US disclosed
WO-2013083743-A1 HYDROLYSABLE SILANES DOW CORNING CORPORATION (US) 2013-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140364627-A1 Hydrolysable Silanes ESD, JMJD6, KDM5A L3MBTL1 4374/4885HPGD 324/4885ATM 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.