SCHEMBL16283147

SCHEMBL16283147

CCO[Si](CCCOC(=O)[C@@H]1C[N@@]1CCC[Si](OCC)(OCC)OCC)(OCC)OCC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15025630 1.00 HPGD (0.31) HPGDATML3MBTL1
SCHEMBL15025583 0.95 L3MBTL1 (0.34) HPGDATML3MBTL1
SCHEMBL16281911 0.94
SCHEMBL15032478 0.92 ALDH1A1 (0.35)
SCHEMBL16307662 0.92 ALDH1A1 (0.35)
SCHEMBL1144589 0.86 CYP3A4 (0.32)
SCHEMBL15025628 0.81 MEN1 (0.41) HPGDATML3MBTL1
SCHEMBL15025256 0.81 MEN1 (0.41) HPGDATML3MBTL1
SCHEMBL16307235 0.79 ALDH1A1 (0.34)
SCHEMBL16283129 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9321792-B2 Hydrolysable silanes DOW CORNING CORPORATION (US) 2016-04-26 US disclosed
US-20140371392-A1 Polymeric Materials Modified By Silanes DOW CORNING EUROPE S.A. (BE) 2014-12-18 US disclosed
US-20140364627-A1 Hydrolysable Silanes DOW SILICONES CORPORATION 2014-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140364627-A1 Hydrolysable Silanes ESD, JMJD6, KDM5A HPGD 324/4885ATM 3332/4885L3MBTL1 4374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.