SCHEMBL1144589

SCHEMBL1144589

CCO[Si](CCCN1CC1C(=O)OC)(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.32
MAPT P10636 2/20 0.32
MMP2 P08253 1/20 0.32
ANPEP P15144 1/20 0.32
BRD4 O60885 1/20 0.30
FKBP1A P62942 1/20 0.30
OGA O60502 1/20 0.30
GAA P10253 2/20 0.30
MGAM O43451 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16307662 0.88 ALDH1A1 (0.35) MAPTFKBP1A
SCHEMBL15032478 0.88 ALDH1A1 (0.35) MAPTFKBP1A
SCHEMBL15025630 0.86 HPGD (0.31)
SCHEMBL16283147 0.86 HPGD (0.31)
SCHEMBL15025583 0.81 L3MBTL1 (0.34) OGAGAAMGAM
SCHEMBL16281911 0.80
SCHEMBL1805198 0.80 MMP2 (0.34) CYP3A4MAPTMMP2ANPEPBRD4
SCHEMBL13472658 0.79 OGA (0.44) CYP3A4MAPTMMP2ANPEPFKBP1A
SCHEMBL29306522 0.78 GBA2 (0.42) CYP3A4MAPTOGAGAA
SCHEMBL29306523 0.76 GBA2 (0.44) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2788363-B1 HYDROLYSABLE SILANES DOW CORNING (US) 2018-04-25 EP disclosed
EP-2963066-B1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE JSR CORP (JP) 2017-12-27 EP disclosed
US-9321792-B2 Hydrolysable silanes DOW CORNING CORPORATION (US) 2016-04-26 US disclosed
US-20160009903-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE JSR CORPORATION (JP) 2016-01-14 US disclosed
EP-2963066-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE JSR Corporation (JP) 2016-01-06 EP disclosed
US-20150322294-A1 POLISHING COMPOSITION FUJIMI INCORPORATED (JP) 2015-11-12 US disclosed
US-8968458-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2015-03-03 US disclosed
US-20140364627-A1 Hydrolysable Silanes DOW SILICONES CORPORATION 2014-12-11 US disclosed
US-20140329976-A1 Treatment Of Filler With Silane DOW CORNING EUROPE S.A. (BE) 2014-11-06 US disclosed
EP-2788435-A1 TREATMENT OF FILLER WITH SILANE Dow Corning Corporation (US) 2014-10-15 EP disclosed
CN-101933103-A Powder for magnetic core, powder magnetic core, and their production methods TOYOTA MOTOR CO LTD 2010-12-29 CN disclosed
US-20100266861-A1 POWDER FOR MAGNETIC CORE, POWDER MAGNETIC CORE AND THEIR PRODUCTION METHODS TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2010-10-21 US disclosed
EP-2221836-A1 POWDER FOR MAGNETIC CORE, POWDER MAGNETIC CORE, AND THEIR PRODUCTION METHODS Toyota Jidosha Kabushiki Kaisha (JP) 2010-08-25 EP disclosed
US-20100151384-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2010-06-17 US disclosed
EP-1927622-B1 Nanocomposite particle and molecular wrapping method TOYOTA CHUO KENKYUSHO KK (JP) 2009-09-02 EP disclosed
US-20090050020-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2009-02-26 US disclosed
EP-1927622-A1 Nanocomposite particle and molecular wrapping method Kabushiki Kaisha Toyota Chuo Kenkyusho (JP) 2008-06-04 EP disclosed
EP-1855159-A1 COMPOSITION FOR UNDERLAYER FILM OF RESIST AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2007-11-14 EP disclosed
US-6773844-B2 HIGH PERFORMANCE WITH A HIGH REACTIVITY KABUSHIKI KAISHA TOSHIBA (JP) 2004-08-10 US disclosed
US-20020061432-A1 Proton conductive film and fuel cell using the same KABUSHIKI KAISHA TOSHIBA (JP) 2002-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140329976-A1 Treatment Of Filler With Silane CD44, ASAH2, COL2A1 CYP3A4 4528/4885MAPT 1688/4885MMP2 381/4885
US-20140364627-A1 Hydrolysable Silanes ESD, JMJD6, KDM5A CYP3A4 2923/4885MAPT 4638/4885MMP2 1237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.