SCHEMBL15025952

SCHEMBL15025952

Cc1cc(-n2c3ccc(C)cc3c3cc(Br)ccc32)cc(-n2c3ccc(C)cc3c3cc(Br)ccc32)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.37
MAPT P10636 3/20 0.36
ALDH1A1 P00352 3/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PIK3CD O00329 1/20 0.35
PIK3CA P42336 1/20 0.35
PIK3CB P42338 1/20 0.35
PIK3CG P48736 1/20 0.35
PDE10A Q9Y233 1/20 0.33
ELANE P08246 2/20 0.33
LMNA P02545 3/20 0.32
HTT P42858 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
CSNK2A2 P19784 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31092475 0.91 MAPT (0.39) DNM1MAPTALDH1A1MAPK1SMN1; SMN2
SCHEMBL4251581 0.89 DNM1 (0.39) DNM1MAPTALDH1A1MAPK1SMN1; SMN2
SCHEMBL11965830 0.89 BCHE (0.36) MAPTMAPK1HTTKMT2AKDM4E
SCHEMBL13232712 0.88 ALDH1A1 (0.36) DNM1MAPTALDH1A1MAPK1PIK3CD
SCHEMBL2721451 0.88 ALDH1A1 (0.41) DNM1MAPTALDH1A1MAPK1SMN1; SMN2
SCHEMBL14845769 0.88 ALDH1A1 (0.41) DNM1MAPTALDH1A1MAPK1SMN1; SMN2
SCHEMBL21028962 0.88 MAPT (0.37) DNM1MAPTALDH1A1MAPK1SMN1; SMN2
SCHEMBL21074933 0.85 MAPT (0.39) MAPTALDH1A1MAPK1HTTKMT2A
SCHEMBL13314099 0.85 BCHE (0.38) MAPTMAPK1SMN1; SMN2LMNAHTT
SCHEMBL5812062 0.85 L3MBTL1 (0.46) DNM1ALDH1A1MAPK1SMN1; SMN2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8981354-B2 Organic light-emitting polymer and device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-03-17 US disclosed
US-20130146852-A1 ORGANIC LIGHT-EMITTING POLYMER AND DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2013-06-13 US disclosed