SCHEMBL5812062

SCHEMBL5812062

Cc1ccc2c(c1)c1cc(Br)ccc1n2-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
KDM4E B2RXH2 3/20 0.46
ATM Q13315 1/20 0.46
PDE10A Q9Y233 1/20 0.44
ALDH1A1 P00352 3/20 0.41
RXFP1 Q9HBX9 1/20 0.41
FGFR1 P11362 1/20 0.41
KMT2A Q03164 4/20 0.40
LMNA P02545 2/20 0.40
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
GAA P10253 1/20 0.39
GFER P55789 1/20 0.39
MEN1 O00255 2/20 0.39
NR1I2 O75469 1/20 0.39
AHR P35869 1/20 0.39
CA9 Q16790 1/20 0.39
HPGD P15428 2/20 0.38
MAPK1 P28482 2/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23774140 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMPDE10AALDH1A1
SCHEMBL4251581 0.91 DNM1 (0.39) KDM4EPDE10AALDH1A1GAAHPGD
SCHEMBL2721451 0.90 ALDH1A1 (0.41) L3MBTL1KDM4EPDE10AALDH1A1GAA
SCHEMBL14845769 0.90 ALDH1A1 (0.41) KDM4EPDE10AALDH1A1RXFP1GAA
SCHEMBL679015 0.89 KDM4E (0.56) L3MBTL1KDM4EATMPDE10AALDH1A1
SCHEMBL29362953 0.89 L3MBTL1 (0.56) L3MBTL1KDM4EATMPDE10AALDH1A1
SCHEMBL181466 0.89 L3MBTL1 (0.56) L3MBTL1KDM4EATMPDE10AALDH1A1
SCHEMBL12362760 0.88 DCTPP1 (0.40) L3MBTL1KDM4EATMPDE10AALDH1A1
SCHEMBL30211017 0.88 L3MBTL1 (0.42) L3MBTL1KDM4EATMPDE10AALDH1A1
SCHEMBL27430096 0.88 L3MBTL1 (0.42) L3MBTL1KDM4EATMPDE10AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020045831-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2020-03-05 WO disclosed
EP-3254317-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-07-31 EP disclosed
EP-2173834-B1 ORGANIC LIGHT-EMITTING DIODES COMPRISING AT LEAST ONE DISILYL COMPOUND SELECTED FROM DISILYLCARBAZOLES, DISILYLDIBENZOFURANS and DISILYLDIBENZOTHIOPHENES UDC IRELAND LTD (IE) 2018-02-14 EP disclosed
US-8921832-B2 Compound and organic device using same LG CHEM, LTD. (KR) 2014-12-30 US disclosed
US-8921832-B2 Compound and organic device using same LG CHEM, LTD. (KR) 2014-12-30 US disclosed
US-20110193074-A1 NOVEL COMPOUND AND ORGANIC DEVICE USING SAME LG CHEM, LTD. (KR) 2011-08-11 US disclosed
US-20110193074-A1 NOVEL COMPOUND AND ORGANIC DEVICE USING SAME LG CHEM, LTD. (KR) 2011-08-11 US disclosed
WO-2009003898-A1 ORGANIC LIGHT-EMITTING DIODES CONTAINING CARBENE TRANSITION METAL COMPLEX EMITTERS AND AT LEAST ONE COMPOUND SELECTED FROM DISILYLCARBAZOLES, DISILYLDIBENZOFURANS, DISILYLDIBENZOTHIOPHENES, DISILYLDIBENZOPHOSPHOLES, DISILYLDIBENZOTHIOPHENE S-OXIDES AND DISILYLDIBENZOTHIOPHENE S,S-DIOXIDES BASF SE (DE) 2009-01-08 WO disclosed
WO-2006096399-A2 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110193074-A1 NOVEL COMPOUND AND ORGANIC DEVICE USING SAME PPOX, AOX1, TRPC6 L3MBTL1 476/4885KDM4E 1876/4885ATM 2754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.