Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31092475 | 0.93 | MAPT (0.39) | MAPTALDH1A1MAPK1DNM1SMN1; SMN2 | |
| SCHEMBL13232712 | 0.89 | ALDH1A1 (0.36) | MAPTALDH1A1MAPK1DNM1HTT | |
| SCHEMBL15025952 | 0.88 | DNM1 (0.37) | MAPTALDH1A1MAPK1DNM1SMN1; SMN2 | |
| SCHEMBL21029364 | 0.87 | MAPT (0.42) | MAPTALDH1A1MAPK1DNM1SMN1; SMN2 | |
| SCHEMBL356742 | 0.81 | ALDH1A1 (0.44) | MAPTALDH1A1MAPK1DNM1SMN1; SMN2 | |
| SCHEMBL12879724 | 0.81 | GSR (0.34) | MAPTALDH1A1DNM1SMN1; SMN2HTT | |
| SCHEMBL2235932 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1MAPK1HTTLMNA | |
| SCHEMBL12635034 | 0.80 | MAPT (0.41) | MAPTALDH1A1DNM1SMN1; SMN2HTT | |
| SCHEMBL4251581 | 0.80 | DNM1 (0.39) | MAPTALDH1A1MAPK1DNM1SMN1; SMN2 | |
| SCHEMBL15595161 | 0.79 | L3MBTL1 (0.48) | MAPTALDH1A1MAPK1DNM1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3493286-A1 | ORGANIC ELECTRONIC MATERIAL | Hitachi Chemical Company, Ltd. (JP) | 2019-06-05 | — | — | EP | disclosed |
| US-20190165293-A1 | ORGANIC ELECTRONIC MATERIAL | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2019-05-30 | — | — | US | disclosed |