Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028248 | 0.94 | TDP1 (0.36) | TSHRALDH1A1PAOXDNM1TDP1 | |
| SCHEMBL15786625 | 0.91 | ALDH1A1 (0.33) | TSHRALDH1A1PAOX | |
| SCHEMBL15028247 | 0.86 | PRMT3 (0.37) | ALDH1A1DNM1TDP1MEN1GAA | |
| SCHEMBL15786595 | 0.85 | TDP1 (0.33) | TSHRALDH1A1PAOXDNM1TDP1 | |
| SCHEMBL10085303 | 0.82 | TSHR (0.39) | TSHRALDH1A1PAOXDNM1TDP1 | |
| SCHEMBL10081267 | 0.78 | ALDH1A1 (0.34) | TSHRALDH1A1PAOXDNM1 | |
| SCHEMBL15786594 | 0.77 | MEN1 (0.34) | ALDH1A1TDP1MEN1GAACYP2C9 | |
| SCHEMBL15150904 | 0.76 | TDP1 (0.38) | TSHRALDH1A1PAOXDNM1TDP1 | |
| SCHEMBL15786628 | 0.76 | PAOX (0.36) | TSHRALDH1A1PAOXDNM1TDP1 | |
| SCHEMBL24172015 | 0.73 | DNM1 (0.47) | DNM1MEN1GAACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013086322-A1 | BRANCHED ALKYL AND CYCLOALKYL TERMINATED BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-06-13 | — | — | WO | disclosed |