Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15786594 | 0.90 | MEN1 (0.34) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL15028248 | 0.88 | TDP1 (0.36) | CYP2C9CYP2C19MEN1GAAKMT2A | |
| SCHEMBL15028245 | 0.86 | TSHR (0.37) | CYP2C9CYP2C19MEN1GAAKMT2A | |
| SCHEMBL15150882 | 0.80 | PRMT3 (0.39) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL15786595 | 0.79 | TDP1 (0.33) | ALDH1A1TDP1DNM1 | |
| SCHEMBL15786625 | 0.77 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL10081264 | 0.75 | ANPEP (0.37) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL2473211 | 0.70 | ANPEP (0.47) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL24246380 | 0.70 | MEN1 (0.45) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL24172349 | 0.69 | DNM1 (0.46) | CYP2C9CYP2C19MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013086322-A1 | BRANCHED ALKYL AND CYCLOALKYL TERMINATED BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-06-13 | — | — | WO | disclosed |