Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540794 | 0.86 | PAOX (0.41) | ANPEPDNM1ALDH1A1MAPTHTT | |
| Phosphoric Acid SCHEMBL14782506 | 0.75 | PRMT3 (0.70) | ANPEPPRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL27165015 | 0.73 | — | — | |
| SCHEMBL28380616 | 0.72 | MMP2 (0.33) | CA1CA2CA12CA9MAPK1 | |
| Phosphoric Acid SCHEMBL28072294 | 0.72 | CA2 (0.47) | ANPEPPRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL15150882 | 0.71 | PRMT3 (0.39) | ANPEPPRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL29406327 | 0.70 | — | — | |
| SCHEMBL5594973 | 0.70 | — | — | |
| SCHEMBL15264079 | 0.70 | ANPEP (0.43) | ANPEPPRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL15028247 | 0.70 | PRMT3 (0.37) | ANPEPPRMT3CARM1PRMT6PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102166215-A | Pharmaceutical composition containing piperazine derivatives | LIYAN WANG | 2011-08-31 | — | — | CN | claimed |
| US-10428019-B2 | Chiral auxiliaries | WAVE LIFE SCIENCES LTD. (SG) | 2019-10-01 | — | — | US | disclosed |
| US-10329318-B2 | Method for the synthesis of phosphorus atom modified nucleic acids | WAVE LIFE SCIENCES LTD. (SG) | 2019-06-25 | — | — | US | disclosed |
| EP-2620428-B1 | ASYMMETRIC AUXILIARY GROUP | WAVE LIFE SCIENCES LTD (SG) | 2019-05-22 | — | — | EP | disclosed |
| US-20180111958-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | WAVE LIFE SCIENCES JAPAN, INC. (JP) | 2018-04-26 | — | — | US | disclosed |
| US-9695211-B2 | Method for the synthesis of phosphorus atom modified nucleic acids | WAVE LIFE SCIENCES JAPAN, INC. (JP) | 2017-07-04 | — | — | US | disclosed |
| US-20160347780-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | WAVE LIFE SCIENCES LTD. (SG) | 2016-12-01 | — | — | US | disclosed |
| EP-2370451-B1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | WAVE LIFE SCIENCES JAPAN INC (JP) | 2016-11-16 | — | — | EP | disclosed |
| US-9394333-B2 | Method for the synthesis of phosphorus atom modified nucleic acids | WAVE LIFE SCIENCES JAPAN (JP) | 2016-07-19 | — | — | US | disclosed |
| EP-2620428-A1 | ASYMMETRIC AUXILIARY GROUP | Chiralgen, Ltd. (JP) | 2013-07-31 | — | — | EP | disclosed |
| US-20130178612-A1 | CHIRAL AUXILIARIES | CHIRALGEN, LTD. (JP) | 2013-07-11 | — | — | US | disclosed |
| US-20110294124-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | WAVE LIFE SCIENCES LTD. (SG) | 2011-12-01 | — | — | US | disclosed |
| EP-2370451-A2 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | Chiralgen, Ltd. (JP) | 2011-10-05 | — | — | EP | disclosed |
| CN-102166215-A | Pharmaceutical composition containing piperazine derivatives | LIYAN WANG | 2011-08-31 | — | — | CN | disclosed |
| WO-2010064146-A2 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | CHIRALGEN, LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |
| WO-2002062811-A2 | IMPROVED METHODS FOR SYNTHESIS OF OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111958-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | PNP, ADAR, NUDT1 | ANPEP 187/4885PRMT3 3566/4885CARM1 3290/4885 |
| US-20130178612-A1 | CHIRAL AUXILIARIES | POLL, PCNA, POLM | ANPEP 621/4885PRMT3 1305/4885CARM1 2191/4885 |
| US-10428019-B2 | Chiral auxiliaries | PCNA, POLL, TYMP | ANPEP 713/4885PRMT3 823/4885CARM1 2387/4885 |
| US-10329318-B2 | Method for the synthesis of phosphorus atom modified nucleic acids | PNP, ADAR, NUDT1 | ANPEP 187/4885PRMT3 3566/4885CARM1 3290/4885 |
| US-20110294124-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | PNP, ADAR, NUDT1 | ANPEP 187/4885PRMT3 3566/4885CARM1 3290/4885 |
| US-20160347780-A1 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | ADAR, PNP, NUDT1 | ANPEP 174/4885PRMT3 2277/4885CARM1 2190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.