SCHEMBL15028273

SCHEMBL15028273

CC(C)c1cccc(C(C)C)c1-c1ccc2c(c1)-c1ccc(B3OC(C)(C)C(C)(C)O3)c3cccc-2c13

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.32
LIPG Q9Y5X9 3/20 0.32
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15028266 0.85 CRHBP (0.35) LPLLIPGCRHBPCRHR2KEAP1
SCHEMBL15028157 0.84 LIPG (0.40) LPLLIPGCRHBPCRHR2KEAP1
SCHEMBL11953434 0.82 LIPG (0.47) LPLLIPGCRHBPCRHR2KEAP1
SCHEMBL22727911 0.81 LIPG (0.42) LPLLIPGCRHBPCRHR2KEAP1
SCHEMBL14680337 0.81
SCHEMBL29709221 0.80 KEAP1 (0.46) LPLLIPGCRHBPCRHR2KEAP1
SCHEMBL961673 0.80 KEAP1 (0.46) LPLLIPGCRHBPCRHR2KEAP1
SCHEMBL30040842 0.80 KEAP1 (0.46) LPLLIPGCRHBPCRHR2KEAP1
SCHEMBL14680543 0.79 LPL (0.34) LPLLIPG
SCHEMBL15028276 0.78 TRPA1 (0.35) LPLLIPGCRHBPCRHR2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170133598-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KK (JP) 2017-05-11 US disclosed
US-20170133598-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KK (JP) 2017-05-11 US disclosed
EP-2788306-B1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KK (JP) 2017-05-03 EP disclosed
US-9590199-B2 Organic compound, organic light emitting device, and image display device CANON KABUSHIKI KAISHA (JP) 2017-03-07 US disclosed
US-9590199-B2 Organic compound, organic light emitting device, and image display device CANON KABUSHIKI KAISHA (JP) 2017-03-07 US disclosed
US-20140374723-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2014-12-25 US disclosed
US-20140374723-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2014-12-25 US disclosed
WO-2013084833-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2013-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170133598-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE OCIAD1, OCIAD2, OXER1 LPL 2620/4885LIPG 3086/4885CRHBP 4698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.