Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028344 | 0.88 | PDE4B (0.50) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL7476215 | 0.80 | ALDH1A1 (0.58) | GPR119ALDH1A1 | |
| SCHEMBL5098530 | 0.78 | KDM1A (0.55) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL5248562 | 0.78 | GPR119 (0.46) | GPR119ALDH1A1 | |
| SCHEMBL3163770 | 0.77 | GPR119 (0.49) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL5201546 | 0.77 | GPR119 (0.48) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL4553177 | 0.76 | GPR119 (0.49) | GPR119ALDH1A1 | |
| SCHEMBL5248566 | 0.76 | JAK2 (0.51) | GPR119 | |
| SCHEMBL3165435 | 0.76 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| Potassium Ion SCHEMBL5201540 | 0.76 | GPR119 (0.48) | PDE4BPDE4DPDE4APDE4CGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013083991-A1 | NOVEL COMPOUNDS AND THEIR USE IN THERAPY | IMPERIAL INNOVATIONS LIMITED (GB) | 2013-06-13 | — | — | WO | disclosed |