Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.32 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.32 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.32 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747679 | 0.90 | CTSL (0.31) | CTSLCTSB | |
| SCHEMBL20980231 | 0.83 | ADRB2 (0.32) | ADRB2 | |
| SCHEMBL24295447 | 0.81 | CTSL (0.34) | CTSLCTSBCHRM2CHRM4CHRM1 | |
| SCHEMBL22375760 | 0.78 | ADRB2 (0.31) | CTSLCTSBADRB2 | |
| SCHEMBL25944862 | 0.77 | ALB (0.36) | — | |
| SCHEMBL23330464 | 0.75 | FOLH1 (0.35) | — | |
| SCHEMBL13707903 | 0.75 | CA2 (0.48) | — | |
| SCHEMBL13707922 | 0.74 | FOLH1 (0.41) | — | |
| SCHEMBL15028483 | 0.73 | — | — | |
| SCHEMBL13337133 | 0.73 | EPHX1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054870-A1 | USE OF IL-7R-ALPHA-GAMMA AGONIST PEPTIDES IN CELL MANUFACTURING | MEDIKINE, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| US-20230357358-A1 | IL-7R-ALPHA-GAMMA BINDING COMPOUNDS | BLUEBIRD VENTURES I, L.P. | 2023-11-09 | — | — | US | disclosed |
| US-20230331801-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS | MEDIKINE, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| US-11746139-B2 | IL-7Rαγc binding compounds | MEDIKINE, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-11718654-B2 | IL-2R-βγ binding compounds | MEDIKINE, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-20220119492-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS AND USES THEREOF | JEFFREY W. AND CHRISTINA R. BIRD TRUST U/A/D | 2022-04-21 | — | — | US | disclosed |
| US-20210253670-A1 | IL-7R-ALPHA-GAMMA BINDING COMPOUNDS | BLUEBIRD VENTURES I, L.P. | 2021-08-19 | — | — | US | disclosed |
| WO-2021158619-A1 | IL-7Rα BINDING COMPOUNDS | MEDIKINE, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021158623-A1 | IL-7Rαγc BINDING COMPOUNDS | MEDIKINE, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| US-20210198336-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS | WS INVESTMENT COMPANY, LLC (23A) | 2021-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331801-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS | IL2RA, IL2, IL15RA | CTSL 1433/4885CTSB 1079/4885CHRM2 3611/4885 |
| US-20210253670-A1 | IL-7R-ALPHA-GAMMA BINDING COMPOUNDS | IL2RA, IL2, IL6ST | CTSL 1524/4885CTSB 990/4885CHRM2 4646/4885 |
| US-11718654-B2 | IL-2R-βγ binding compounds | IL2RA, IL2, IL1RN | CTSL 1683/4885CTSB 1126/4885CHRM2 3988/4885 |
| US-20210198336-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS | IL2RA, IL2, IL15RA | CTSL 1433/4885CTSB 1079/4885CHRM2 3611/4885 |
| US-11746139-B2 | IL-7Rαγc binding compounds | IL2RA, IL23R, IL6ST | CTSL 1726/4885CTSB 1028/4885CHRM2 4763/4885 |
| US-20220119492-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS AND USES THEREOF | IL2RA, IL2, IL15RA | CTSL 1317/4885CTSB 948/4885CHRM2 4108/4885 |
| US-20230357358-A1 | IL-7R-ALPHA-GAMMA BINDING COMPOUNDS | IL2RA, IL2, IL6ST | CTSL 1524/4885CTSB 990/4885CHRM2 4646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.