SCHEMBL15028484

SCHEMBL15028484

CNC(=O)C(CCN=[N+]=[N-])NC

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BMP1 P13497 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17906289 0.84 CTSL (0.32) —
SCHEMBL27041677 0.83 GGH (0.33) —
SCHEMBL18028045 0.83 — —
SCHEMBL27041682 0.83 GGH (0.33) —
SCHEMBL15028483 0.81 — —
SCHEMBL15728239 0.74 — —
SCHEMBL18721927 0.73 MMP2 (0.30) —
SCHEMBL15251520 0.73 MMP2 (0.30) —
SCHEMBL15706851 0.71 FOLH1 (0.32) —
SCHEMBL13448062 0.71 FOLH1 (0.39) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160194391-A1 ANTIBODY DERIVATIVES ALLOZYNE, INC. 2016-07-07 — — US disclosed
US-20140127209-A1 ANTIBODY DERIVATIVES MEDIMMUNE LIMITED (GB) 2014-05-08 — — US disclosed
US-20140127209-A1 ANTIBODY DERIVATIVES MEDIMMUNE LIMITED (GB) 2014-05-08 — — US disclosed
WO-2012032181-A9 ANTIBODY DERIVATIVES ALLOZYNE, INC (US) 2013-06-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160194391-A1 ANTIBODY DERIVATIVES IL23R, IL6, IL2 BMP1 2999/4885
US-20140127209-A1 ANTIBODY DERIVATIVES IL23R, IL6, IL2 BMP1 2970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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