SCHEMBL18721927

SCHEMBL18721927

CNC(=O)C(CCN=[N+]=[N-])OC(C)=O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MMP2 P08253 1/20 0.30
▸ ANPEP P15144 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15251520 1.00 MMP2 (0.30) MMP2ANPEP
SCHEMBL16271230 0.84 TRPV1 (0.33) MMP2ANPEP
SCHEMBL19501730 0.84 — —
SCHEMBL17586046 0.84 TRPV1 (0.33) MMP2ANPEP
SCHEMBL23690559 0.80 TSHR (0.30) —
SCHEMBL15028484 0.73 BMP1 (0.30) —
SCHEMBL11267349 0.68 TDP1 (0.46) —
SCHEMBL20051989 0.68 TRPV1 (0.36) —
SCHEMBL25516983 0.66 NOS2 (0.39) —
SCHEMBL13415809 0.64 TSHR (0.48) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9616079-B2 Aminoglycosides and uses thereof in treating genetic disorders TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2017-04-11 — — US disclosed
WO-2012066546-A1 AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2012-05-24 — — WO disclosed
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