Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 8/20 | 0.44 |
| ▸ | GLA | P06280 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2055238 | 0.75 | APP (0.67) | NPC1RAB9AKMT2AMEN1APP | |
| SCHEMBL16436146 | 0.73 | RAB9A (0.67) | NPC1RAB9AKMT2AMEN1APP | |
| SCHEMBL12727643 | 0.72 | TOP2A (0.59) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL12727644 | 0.72 | HCAR3 (0.51) | GAAMAPTALDH1A1 | |
| SCHEMBL12727662 | 0.68 | MMP2 (0.64) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL12727590 | 0.68 | GAA (0.60) | NPC1RAB9AKMT2AMEN1APP | |
| SCHEMBL25062712 | 0.67 | SMN1; SMN2 (0.50) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL21471952 | 0.66 | RAB9A (0.68) | NPC1RAB9AKMT2AMEN1APP | |
| SCHEMBL7208787 | 0.66 | RAB9A (0.71) | NPC1RAB9AKMT2AMEN1APP | |
| SCHEMBL5184949 | 0.66 | RAB9A (0.64) | NPC1RAB9AKMT2AMEN1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150037253-A1 | METAL COMPLEXES AS IMAGING AGENTS | THE UNIVERSITY OF MELBOURNE (AU) | 2015-02-05 | — | — | US | disclosed |
| WO-2013082661-A1 | METAL COMPLEXES AS IMAGING AGENTS | THE UNIVERSITY OF MELBOURNE (AU) | 2013-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150037253-A1 | METAL COMPLEXES AS IMAGING AGENTS | APBA1, TBCB, PSEN1 | NPC1 840/4885RAB9A 3396/4885KMT2A 3593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.