Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | COMT | P21964 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15030883 | 0.94 | FAAH (0.37) | ALDH1A1FAAHHSP90AA1PKMHTT | |
| SCHEMBL15030671 | 0.93 | FAAH (0.36) | ALDH1A1FAAHHSP90AA1PKMHTT | |
| SCHEMBL16186675 | 0.92 | ALDH1A1 (0.39) | ALDH1A1FAAHHSP90AA1PKMHTT | |
| SCHEMBL15030759 | 0.92 | ALDH1A1 (0.39) | ALDH1A1FAAHHSP90AA1PKMHTT | |
| SCHEMBL15030755 | 0.91 | ALDH1A1 (0.38) | ALDH1A1FAAHHSP90AA1PKMHTT | |
| SCHEMBL16186674 | 0.90 | FAAH (0.36) | ALDH1A1FAAHHSP90AA1PKMHTT | |
| SCHEMBL15030665 | 0.90 | FAAH (0.34) | ALDH1A1FAAHHSP90AA1PKMHTT | |
| SCHEMBL15030757 | 0.90 | ALDH1A1 (0.41) | ALDH1A1FAAHHSP90AA1PKMHTT | |
| SCHEMBL16186705 | 0.88 | ALDH1A1 (0.33) | ALDH1A1FAAHHSP90AA1PKMHTT | |
| SCHEMBL15030882 | 0.87 | MEN1 (0.34) | ALDH1A1FAAHHSP90AA1PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10396297-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2019-08-27 | — | — | US | disclosed |
| US-10305040-B2 | Spiro dihydroacridine derivatives and the use thereof as materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2019-05-28 | — | — | US | disclosed |
| US-20170331053-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| US-20170331053-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| EP-2780325-B1 | SPIRO-DIHYDROACRIDINE DERIVATIVES AND THEIR USE AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-02-03 | — | — | EP | disclosed |
| US-20140316134-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140316134-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2013083216-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2013-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10305040-B2 | Spiro dihydroacridine derivatives and the use thereof as materials for organic electroluminescence devices | SORD, ALDH1A1, SDHA | ALDH1A1 2/4885FAAH 4733/4885HSP90AA1 1096/4885 |
| US-10396297-B2 | Materials for electronic devices | DDT, PNMT, COMT | ALDH1A1 423/4885FAAH 1967/4885HSP90AA1 4358/4885 |
| US-20170331053-A1 | MATERIALS FOR ELECTRONIC DEVICES | DDT, PNMT, COMT | ALDH1A1 423/4885FAAH 1967/4885HSP90AA1 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.