Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37429 | 0.93 | RXFP1 (0.35) | L3MBTL1RXFP1 | |
| SCHEMBL15032129 | 0.92 | L3MBTL1 (0.34) | L3MBTL1SIGMAR1RXFP1 | |
| SCHEMBL15032128 | 0.89 | L3MBTL1 (0.35) | L3MBTL1SIGMAR1RXFP1 | |
| SCHEMBL15032115 | 0.88 | RXFP1 (0.32) | RXFP1KDM4EALDH1A1 | |
| SCHEMBL15032117 | 0.86 | RXFP1 (0.34) | L3MBTL1RXFP1 | |
| SCHEMBL14998149 | 0.86 | RXFP1 (0.32) | L3MBTL1RXFP1 | |
| SCHEMBL14834056 | 0.85 | RXFP1 (0.31) | RXFP1 | |
| SCHEMBL46100 | 0.84 | EPHX2 (0.34) | EPHX2SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL15032120 | 0.84 | RXFP1 (0.34) | L3MBTL1RXFP1 | |
| SCHEMBL15032124 | 0.84 | L3MBTL1 (0.39) | L3MBTL1SIGMAR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575469-B1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-14 | — | — | EP | disclosed |
| US-9771365-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-26 | — | — | US | disclosed |
| US-9771365-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-26 | — | — | US | disclosed |
| EP-2575472-B1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA USING SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| EP-2575449-B1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-04-27 | — | — | EP | disclosed |
| US-20150259345-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA LIMITED (GB) | 2015-09-17 | — | — | US | disclosed |
| US-20140011676-A1 | 1, 8 -DIAZASPIRO [4.5] DECANE- 2, 4 -DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-09 | — | — | US | disclosed |
| US-20140011676-A1 | 1, 8 -DIAZASPIRO [4.5] DECANE- 2, 4 -DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-09 | — | — | US | disclosed |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130150394-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-13 | — | — | US | disclosed |
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-12-08 | — | — | US | disclosed |
| WO-2011151194-A1 | 1, 8 -DIAZASPIRO [4.5] DECANE- 2, 4 -DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151248-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151247-A2 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | DDT, THOP1, KCNH1 | L3MBTL1 2885/4885EPHX2 480/4885SIGMAR1 194/4885 |
| US-20130150394-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, GAP43 | L3MBTL1 366/4885EPHX2 662/4885SIGMAR1 2633/4885 |
| US-20140011676-A1 | 1, 8 -DIAZASPIRO [4.5] DECANE- 2, 4 -DIONE DERIVATIVES USEFUL AS PESTICIDES | DDT, DDO, DPP7 | L3MBTL1 1253/4885EPHX2 2827/4885SIGMAR1 1986/4885 |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | DDT, CIP2A, CYP51A1 | L3MBTL1 1693/4885EPHX2 1618/4885SIGMAR1 2570/4885 |
| US-20150259345-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | DDT, THOP1, KCNH1 | L3MBTL1 2662/4885EPHX2 503/4885SIGMAR1 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.