Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.72 |
| ▸ | MEN1 | O00255 | 11/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.72 |
| ▸ | HPGD | P15428 | 11/20 | 0.72 |
| ▸ | BLM | P54132 | 10/20 | 0.72 |
| ▸ | MAPT | P10636 | 9/20 | 0.72 |
| ▸ | SAE1 | Q9UBE0 | 9/20 | 0.72 |
| ▸ | UBA2 | Q9UBT2 | 9/20 | 0.72 |
| ▸ | HTT | P42858 | 6/20 | 0.72 |
| ▸ | POLB | P06746 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | CASP3 | P42574 | 4/20 | 0.72 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.72 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.72 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8168066 | 0.86 | ALDH1A1 (0.53) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15032607 | 0.84 | KDM4E (1.00) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15032605 | 0.82 | SAE1 (0.76) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15032610 | 0.81 | SAE1 (0.72) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4787894 | 0.79 | KDM4E (0.68) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4788160 | 0.78 | ALDH1A1 (0.77) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8147117 | 0.70 | KDM4E (0.75) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL15256874 | 0.68 | SAE1 (1.00) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4785628 | 0.67 | SAE1 (0.76) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8164257 | 0.67 | KDM4E (0.63) | KDM4EMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |
| US-9073941-B2 | Compounds and methods for treating tuberculosis infection | ACADEMIA SINICA (TW) | 2015-07-07 | — | — | US | disclosed |
| US-9073941-B2 | Compounds and methods for treating tuberculosis infection | ACADEMIA SINICA (TW) | 2015-07-07 | — | — | US | disclosed |
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | ACADEMIA SINICA (TW) | 2013-06-20 | — | — | US | disclosed |
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | ACADEMIA SINICA (TW) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | TALDO1, PGD, DLD | KDM4E 903/4885MEN1 3731/4885KMT2A 2118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.