Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15032500 | 0.93 | SHMT2 (0.60) | ALDH1A1HTTMEN1MAPTKMT2A | |
| SCHEMBL15032501 | 0.90 | MAPT (0.53) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL15032636 | 0.90 | SHMT2 (0.50) | ALDH1A1HTTMEN1MAPTKMT2A | |
| SCHEMBL10198368 | 0.87 | KMT2A (0.59) | ALDH1A1MEN1MAPTKMT2ARAB9A | |
| SCHEMBL15032637 | 0.85 | LMNA (0.52) | ALDH1A1MEN1MAPTKMT2ARAB9A | |
| SCHEMBL15032502 | 0.82 | MAPT (0.51) | ALDH1A1MEN1MAPTKMT2ARAB9A | |
| SCHEMBL15032503 | 0.81 | MEN1 (0.67) | ALDH1A1MEN1MAPTKMT2ARAB9A | |
| SCHEMBL15032504 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2ARAB9APOLB | |
| SCHEMBL855488 | 0.69 | HSD17B10 (0.48) | ALDH1A1HTTMEN1KMT2ASHMT2 | |
| SCHEMBL741345 | 0.68 | HSD17B10 (0.46) | ALDH1A1MEN1KMT2ASHMT2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073941-B2 | Compounds and methods for treating tuberculosis infection | ACADEMIA SINICA (TW) | 2015-07-07 | — | — | US | disclosed |
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | ACADEMIA SINICA (TW) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | TALDO1, PGD, DLD | ALDH1A1 674/4885HTT 4149/4885MEN1 3731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.