Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1503131 | 0.78 | BCHE (0.39) | CA12PPARGKMT2A | |
| SCHEMBL1503319 | 0.76 | KMT2A (0.38) | MAPTLMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL1503138 | 0.73 | KMT2A (0.48) | MAPTCA12L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL12444364 | 0.72 | ALOX5 (0.40) | MAPTLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL1503187 | 0.71 | ALDH1A1 (0.41) | MAPTLMNANPC1RAB9AKMT2A | |
| SCHEMBL1503317 | 0.70 | KMT2A (0.35) | MAPTLMNAKMT2A | |
| SCHEMBL15746657 | 0.70 | KDM4E (0.41) | L3MBTL1ARKMT2A | |
| SCHEMBL1503211 | 0.69 | KDM4E (0.37) | L3MBTL1PLA2G1BATG4BGRM5AR | |
| SCHEMBL15746784 | 0.68 | BCHE (0.37) | PPARGARKMT2A | |
| SCHEMBL1503203 | 0.68 | L3MBTL1 (0.40) | MAPTLMNAL3MBTL1ARRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300433-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | Ambrilia Biopharma Inc. (CA) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009146555-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | AMBRILIA BIOPHARMA INC. (CA) | 2009-12-10 | — | — | WO | disclosed |