Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 6/20 | 0.53 |
| ▸ | FAAH | O00519 | 5/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.50 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12965909 | 0.86 | ACHE (0.57) | POLBRAB9ANPC1ACHEFAAH | |
| SCHEMBL14032560 | 0.86 | HRH3 (0.56) | POLBRAB9ANPC1ACHEFAAH | |
| SCHEMBL15033033 | 0.85 | FAAH (0.52) | POLBRAB9ANPC1ACHEFAAH | |
| SCHEMBL14032652 | 0.84 | FAAH (0.57) | POLBRAB9AACHEFAAHBCHE | |
| SCHEMBL19190328 | 0.83 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL14032557 | 0.81 | HRH3 (0.58) | POLBRAB9AACHEFAAHBCHE | |
| SCHEMBL19190327 | 0.81 | POLB (0.54) | POLBACHEFAAHBCHES1PR5 | |
| SCHEMBL28667789 | 0.80 | HRH3 (0.55) | RAB9ANPC1ACHES1PR5HRH3 | |
| SCHEMBL23775592 | 0.80 | RAB9A (0.58) | RAB9ANPC1ACHES1PR5HRH3 | |
| SCHEMBL15400302 | 0.80 | SIGMAR1 (0.54) | ACHEFAAHHRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130157981-A1 | HETEROCYCLIC COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157981-A1 | HETEROCYCLIC COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | SCNN1B, SCNN1A, TRPM5 | POLB 3779/4885RAB9A 4096/4885NPC1 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.