Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334039 | 0.92 | ROCK1 (0.46) | MAPTSMN1; SMN2ROCK1NPC1MAPK1 | |
| SCHEMBL16267295 | 0.89 | RORC (0.41) | MAPTSMN1; SMN2ROCK1L3MBTL1ALDH1A1 | |
| SCHEMBL16274458 | 0.86 | ALDH1A1 (0.54) | MAPTSMN1; SMN2ROCK1L3MBTL1ALDH1A1 | |
| SCHEMBL2458432 | 0.84 | MAPT (0.44) | MAPTSMN1; SMN2ROCK1NPC1MAPK1 | |
| SCHEMBL2675480 | 0.84 | MAPT (0.48) | MAPTSMN1; SMN2ROCK1L3MBTL1ALDH1A1 | |
| SCHEMBL15016540 | 0.82 | HTR7 (0.51) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL4429154 | 0.82 | REN (0.43) | MAPTSMN1; SMN2ROCK1NPC1MAPK1 | |
| SCHEMBL23455373 | 0.81 | MAPT (0.60) | MAPTSMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL30073954 | 0.80 | MAPT (0.49) | MAPTSMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL23455339 | 0.80 | MAPT (0.49) | MAPTSMN1; SMN2NPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9107848-B2 | Coupler with cationic 7-amino-1,2,3,4-tetrahydroquinoline structure, dyeing composition comprising same, processes and uses | L'OREAL (FR) | 2015-08-18 | — | — | US | disclosed |
| US-20140352713-A1 | COUPLER WITH CATIONIC 7-AMINO-1,2,3,4-TETRAHYDROQUINOLINE STRUCTURE, DYEING COMPOSITION COMPRISING SAME, PROCESSES AND USES | L'OREAL (FR) | 2014-12-04 | — | — | US | disclosed |
| WO-2013087931-A1 | COUPLER WITH CATIONIC 7-AMINO-1,2,3,4-TETRAHYDROQUINOLINE STRUCTURE, DYEING COMPOSITION COMPRISING SAME, PROCESSES AND USES | L'OREAL (FR) | 2013-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140352713-A1 | COUPLER WITH CATIONIC 7-AMINO-1,2,3,4-TETRAHYDROQUINOLINE STRUCTURE, DYEING COMPOSITION COMPRISING SAME, PROCESSES AND USES | KRT18, PRMT7, ARGLU1 | MAPT 946/4885SMN1; SMN2 4633/4885ROCK1 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.