Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | STAT5B | P51692 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357919 | 0.69 | MGLL (0.46) | MGLLALDH1A1FAAHDAGLACNR2 | |
| SCHEMBL8717854 | 0.69 | NPC1 (0.46) | CYP1A2 | |
| SCHEMBL16732072 | 0.67 | TSHR (0.45) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL16732236 | 0.67 | PPARG (0.44) | CYP1A2 | |
| SCHEMBL2183633 | 0.66 | MGLL (0.85) | MGLLALDH1A1FAAHDAGLATRPV1 | |
| Benzene SCHEMBL8717860 | 0.66 | TSHR (0.48) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1792881 | 0.66 | TSHR (0.48) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9643255 | 0.66 | MGLL (0.59) | MGLLALDH1A1FAAHDAGLATRPV1 | |
| SCHEMBL28817737 | 0.66 | SLC1A3 (0.43) | ALDH1A1MEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17317282 | 0.65 | MTNR1A (0.47) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611284-B2 | Prostaglandin-bisphosphonate conjugate compounds, methods of making same, and uses thereof | SIMON FRASER UNIVERSITY (CA) | 2017-04-04 | — | — | US | disclosed |
| US-20130157984-A1 | PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, METHODS OF MAKING SAME, AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157984-A1 | PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, METHODS OF MAKING SAME, AND USES THEREOF | PTGES, PTGFR, PTGIS | MGLL 871/4885ALDH1A1 1462/4885FAAH 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.