Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15038852 | 0.80 | HTR2A (0.43) | HTR2AMGLLALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15033721 | 0.79 | CNR2 (0.43) | HTR2AMGLLALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12064912 | 0.74 | CNR2 (0.43) | HTR2AMGLLALDH1A1MAPTCYP19A1 | |
| SCHEMBL6403448 | 0.73 | CYP19A1 (0.40) | HTR2AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6403444 | 0.73 | CYP19A1 (0.40) | HTR2AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7418355 | 0.72 | HTR2A (0.57) | HTR2AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7296368 | 0.72 | MEN1 (0.48) | HTR2AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7296372 | 0.72 | MEN1 (0.48) | HTR2AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29592309 | 0.71 | HTR2A (0.62) | HTR2AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL389680 | 0.70 | ALDH1A1 (0.52) | HTR2AMGLLALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611284-B2 | Prostaglandin-bisphosphonate conjugate compounds, methods of making same, and uses thereof | SIMON FRASER UNIVERSITY (CA) | 2017-04-04 | — | — | US | disclosed |
| US-20130157984-A1 | PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, METHODS OF MAKING SAME, AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157984-A1 | PROSTAGLANDIN-BISPHOSPHONATE CONJUGATE COMPOUNDS, METHODS OF MAKING SAME, AND USES THEREOF | PTGES, PTGFR, PTGIS | HTR2A 3244/4885MGLL 871/4885ALDH1A1 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.