Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18722105 | 0.81 | MAOB (0.45) | MAOBMAOASLC6A3CHRNA1CHRNG | |
| SCHEMBL21935248 | 0.70 | ACHE (0.59) | MAOBMAOASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3587056 | 0.66 | MAOB (0.52) | MAOBMAOASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL11549695 | 0.66 | MAOB (0.38) | MAOBMAOASLC6A2SLC6A3CHRNA1 | |
| SCHEMBL8747865 | 0.66 | OPRM1 (0.41) | MAOBMAOASLC6A2SLC6A3CHRNA1 | |
| SCHEMBL8747847 | 0.66 | MAOB (0.38) | MAOBMAOASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8297045 | 0.64 | ACHE (0.44) | MAOBMAOASLC6A2SLC6A3CHRNA1 | |
| SCHEMBL27959942 | 0.63 | MAOB (0.39) | MAOBMAOASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL15043554 | 0.63 | MGAT2 (0.33) | MAOBMAOASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL21935244 | 0.62 | ALDH1A1 (0.46) | MAOBMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |