Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.71 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.71 |
| ▸ | AR | P10275 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | ESR1 | P03372 | 1/20 | 0.71 |
| ▸ | TST | Q16762 | 1/20 | 0.71 |
| ▸ | VDR | P11473 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12516466 | 0.92 | VDR (0.81) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL29768278 | 0.86 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL5284953 | 0.86 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL285664 | 0.86 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL6651542 | 0.86 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL285663 | 0.86 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL5917328 | 0.86 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL6651547 | 0.86 | ALDH1A1 (0.75) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL19733279 | 0.85 | ALDH1A1 (0.74) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1249402 | 0.85 | ALDH1A1 (0.74) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9775903-B2 | 1-deoxy analogs of 1,25-dihydroxyvitamin D3 compounds | JOHNS HOPKINS UNIVERSITY (US) | 2017-10-03 | — | — | US | disclosed |
| US-20130157987-A1 | 1-DEOXY ANALOGS OF 1,25-DIHYDROXYVITAMIN D3 COMPOUNDS | JOHNS HOPKINS UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157987-A1 | 1-DEOXY ANALOGS OF 1,25-DIHYDROXYVITAMIN D3 COMPOUNDS | CYP24A1, CYP2R1, CYP27B1 | ALDH1A1 288/4885ALOX15 394/4885CYP3A4 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.