SCHEMBL15048637

SCHEMBL15048637

C=CCc1ccccc1O[PH](=O)Oc1ccccc1CC=C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 5/20 0.47
HTR1A P08908 4/20 0.47
ADRA2A P08913 4/20 0.47
ADRA2B P18089 4/20 0.47
NISCH Q9Y2I1 1/20 0.47
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 3/20 0.45
ADRB2 P07550 3/20 0.42
ADRB1 P08588 3/20 0.42
LMNA P02545 2/20 0.42
KCNH2 Q12809 2/20 0.42
ADRB3 P13945 1/20 0.42
SLC6A2 P23975 1/20 0.42
BDKRB2 P30411 1/20 0.42
SLC6A4 P31645 1/20 0.42
ADRA1A P35348 1/20 0.42
HTR2B P41595 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15048638 0.87 ALDH1A1 (0.47) ADRA2CHTR1AADRA2AADRA2BNISCH
SCHEMBL6849991 0.84 GABRA1 (0.44) ADRA2CHTR1AADRA2AADRA2BNISCH
SCHEMBL13002811 0.81 ALDH1A1 (0.36) ADRA2CHTR1AADRA2AADRA2BNISCH
Formaldehyde SCHEMBL4291615 0.80 ICAM1 (0.48) ADRA2CHTR1AADRA2AADRA2BNISCH
SCHEMBL3955458 0.79 ALDH1A1 (0.50) ADRA2CHTR1AADRA2AADRA2BNISCH
SCHEMBL88415 0.79 ALDH1A1 (0.50) ADRA2CHTR1AADRA2AADRA2BNISCH
SCHEMBL2822981 0.78 L3MBTL1 (0.50) ADRA2CADRA2AADRA2BNISCHKDM4E
Water SCHEMBL8939878 0.78 ALDH1A1 (0.49) ADRA2CHTR1AADRA2AADRA2BNISCH
Ethylene SCHEMBL173231 0.78 ALDH1A1 (0.49) ADRA2CHTR1AADRA2AADRA2BNISCH
SCHEMBL3744643 0.78 ALDH1A1 (0.49) ADRA2CHTR1AADRA2AADRA2BNISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470741-B2 oil-based concentrate which is homogenous for at least 24 hours and which emulsifies readily on dilution into water CRODA AMERICAS LLC (US) 2013-06-25 US claimed